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When Dr. Kavita Rao develops a controversial mutant cure, Professor Charles Xaviers X-Men, the aggressive Wolverine, conflicted Beast and newly returned Kitty Pryde, led by Cyclops and Emma Frost, once again find themselves battling against science, prejudice and a mysterious new foe named Ord! Can the X-Men protect the mutants of the world against this powerful new alien menace and the concoction that threatens to rid them of their unique abilities?